R437A R437A, also known as ISCEON® MO49Plus™, is an HFC blend suitable for use as a retrofit replacement refrigerant for R12 in automotive air conditioning and stationary refrigeration systems, and for replacing HCFC-containing refrigerant blends (e.g., R401A, R401B and R409A) in medium and high temperature stationary refrigeration systems.

R437A is compatible with traditional and new lubricants; in most cases no change of lubricant is required during retrofit.


Common Applications:


Industrial Refrigeration


Residential & Light Air Conditioning


Industrial/Commercial Air Conditioning DX Chillers


Mobile Air Conditioning


Replacement for: R12, HCFC blends
Retrofit gas or design for new equipment? R437A is suitable as a "drop-in" retrofit gas for R12 and other HCFC blends.
Other alternatives / replacements: R424A, R427A, R438A
Compatible lubricants: MO, AB, POE


Environmental Impact

Ozone Depletion Potential (ODP) 0
Ozone Depletion Potential (Rating)
Global Warming Potential (GWP) 1805
Global Warming Potential (Rating)


Safety Information

ASHRAE Safety Group (2013) A1
ASHRAE Flammability No
ASHRAE Toxicity No


Supply Modes & Package Specifications
We offer this refrigerant gas in a range of package sizes to suit a wide range of applications. Typically, this will include both cylinders and drum tanks.

Further Information
ISCEON® is a registered trademark of E.I. du Pont de Nemours & Company.